When that extra helping of comfort, space and personal service is important, a business class flight is the answer! If you're looking to book a business class flight from Brisbane to South America, then you've come to the right place. We've gathered all our business class airfares from Brisbane to South America together, so that you can browse through all of them at your leisure and choose the flight that best serves your needs and budget! Forgive us the pun, but... that's the business!